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Local Intra-Arterial Thrombolysis in Acute Ischemic Stroke
Stroke 29:1894-1900, Gonner,F.,et al, 1998
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Article Abstract
We performed a retrospective analysis of the prognostic factors in patient treated with local intra-arterial thrombolysis(LIT).The purpose of this study was to evaluate the safety and efficacy of LIT using urokinase in patients with acute ischemic stroke of the anterior or posterior circulation and to determine the influence of clinical and radiological parameters on outcome.LIT was not efficacious in patients with MCA and BA occlusions with the initial NIHSS score was less than 20 and when treated within 4 hours.It is of limited value in patients with distal ICA occlusions.
 
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basilar artery occlusion
cerebrovascular accident
cerebrovascular accident,acute management of
cerebrovascular accident,thrombolytic agents in treatment
fibrinolytic agents
fibrinolytic agents,intra-arterial local infusion
middle cerebral artery,occlusion of
recanalization,arterial
treatment of neurologic disorder
urokinase

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